USMLE USMLE : United States Medical Licensing Examination

  • Exam Code: USMLE
  • Exam Name: United States Medical Licensing Examination
  • Updated: Jun 01, 2026
  • Q & A: 400 Questions and Answers

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USMLE USMLE Exam Syllabus Topics:

TopicDetails
Topic 1
  • Adverse effects of drugs on the hematologic and lymphoreticular systems
  • Disorders associated with immunodeficiency
Topic 2
  • Deficiency primarily of humoral immunity
  • Immunologic and inflammatory disorders
Topic 3
  • Cranial and peripheral nerve disorders
  • Cellular basis of the immune response and immunologic mediators
Topic 4
  • Biology of tissue response to disease
  • Disorders of balance and spatial orientation
Topic 5
  • Eating disorders and impulse control disorders
  • Pharmacodynamic and pharmacokinetic processes

Reference: http://www.usmle.org/step-1/#question-formats

USMLE Step 2 is open to all medical students and graduates who have successfully passed the USMLE Step 1. The Step 2 exam assesses the candidates' medical knowledge, skills, and understanding of clinical science essential for patient treatment and care, health promotion and disease prevention.

USMLE Step 3 is open to candidates who already hold their USMLE Step 1 and Step 2 certificates. Step 3 is a two-day exam that assesses whether candidates are able apply medical knowledge and understanding of biomedical and clinical science essential to unsupervised medical practice. This is the final USMLE exam which leads to the license to practice medicine without supervision - the ultimate goal of medical students and professionals willing to practice medicine in the United States. Step 3 represents the final assessment of physicians assuming independent responsibility for delivering general medical care.

USMLE Step 1 is a one-day (8 hours) examination. It includes 322 multiple-choice questions divided into 7 blocks of 46 items (60 minutes are given for completion of each block).

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